Understanding the Origins and Devastating Effects of XDR-TB
Newsweek published an Web Exclusive interview yesterday on the emergence of XDR-TB as a global public health threat. Prompted by James Nachtwey’s photos and XDRTB.org, Newsweek’s Anne Underwood spoke with , director of the World Health Organization’s Stop TB Department, and , world ambassador for WHO’s Stop TB Partnership.
While the interview covers many important issues, I found the following exchange of particular interest:
Does the existence of XDR mean we’ve failed at fighting TB?
Raviglione: It’s a sign that things have gone wrong in many places, due to mismanagement of cases, careless prescriptions of drugs, incorrect regimens and the lack of support and follow-up with patients. Together, these problems have created MDR- and XDR-TB. If we do not turn the tide by establishing good, basic TB control and care practices, it will lead to an increase in XDR-TB.
Cataldi: Drug companies are not very interested in TB, because the drugs are so cheap. By contrast, antiretroviral cocktails for HIV are a gigantic business. The drugs we use for TB now are 50 years old. Further dissemination of XDR-TB may stop all progress we’ve made in recent years in control [of normal TB].
It is staggering to think that a disease which continues to infect millions worldwide can be so forgotten and, in the broader picture, ignored. Sharing the story of XDR-TB feels even more crucial.
Read the whole interview here.